TSA Guidelines for Flying with Prescription Medications: What You Need to Know in 2025

Trying to fly with your prescription meds shouldn’t feel like a security test. But too many travelers get stopped, questioned, or even have their medicine taken away-just because they didn’t know the rules. The good news? The TSA lets you bring almost all prescription medications on board, no matter how much you need. The bad news? A lot of people still mess it up. Here’s what actually works, based on the latest rules from TSA, CDC, and airlines as of late 2024.

Medications Don’t Count Toward the 3-1-1 Liquid Rule

You’ve seen the signs: liquids must be 3.4 ounces or less, all in one clear quart-sized bag. That rule? It doesn’t apply to your prescription meds. Not insulin. Not your daily heart pill in liquid form. Not your eye drops or saline solution. Even if you’re carrying a 6-ounce bottle of liquid painkiller, you’re still allowed. The TSA explicitly says medically necessary liquids are exempt from the 3-1-1 rule. That means no squeezing your meds into tiny travel bottles just to fit the limit.

But here’s the catch: you still have to declare them. When you get to the security checkpoint, tell the officer you have medications. Don’t wait for them to ask. Pull them out of your bag and place them in a bin by themselves. This isn’t optional-it cuts down delays and avoids confusion. In 2023, nearly 80% of medication-related security delays happened because travelers didn’t proactively declare their meds.

Keep Them in Original Packaging (Even If It’s Bulky)

You might think tossing your pills into a pill organizer makes your bag lighter. And it does. But it also makes TSA’s job harder. Official guidance from the CDC and United Airlines says: keep meds in their original bottles. Why? Because the label shows your name, the drug name, dosage, and prescribing doctor. If your name on the bottle doesn’t match your ID-even if it’s just a missing middle initial-you could get held up for 10 minutes or more while they verify everything.

That’s not a myth. United Airlines’ internal data shows that 78% of medication delays in 2023 were caused by name mismatches. One traveler had a bottle labeled “J. Smith,” but her ID said “Jennifer Smith.” The officer didn’t know if it was her medicine or someone else’s. That’s why even if your bottles are huge, just bring them. If space is tight, pack them in your carry-on, not your checked bag. Checked luggage can get lost, delayed, or even exposed to extreme temperatures that ruin your meds.

Never Put Medication in Checked Luggage

This one’s simple: never put your prescriptions in your checked bag. Not even one pill. United Airlines, American, Delta, and Alaska all have the same policy: carry-on only. Why? Because people have lost life-saving insulin, seizure meds, and heart medications when their bags got delayed or misrouted. In 2022, a passenger’s insulin was destroyed in checked baggage during a layover. He ended up in the ER. Since then, nearly every major U.S. airline has made carry-on-only mandatory for all medications.

If you’re worried about space, use a small toiletry bag just for your meds. Or even a ziplock with your bottles neatly lined up. TSA doesn’t care how you organize them-as long as you can show them clearly and they’re labeled.

CBD and THC Products Are a Minefield

This is where things get messy. If your CBD oil says “0.3% THC or less,” you might think it’s fine. But TSA still confiscates it. Why? Because federal law still classifies marijuana as illegal-even if your state allows it. The TSA follows federal rules, not state ones. And while products with less than 0.3% THC are technically legal under the 2018 Farm Bill, TSA officers aren’t trained to test THC levels on the spot. They see “CBD,” they see “marijuana,” and they err on the side of caution.

According to a 2024 Government Accountability Office report, over 14,000 CBD products were confiscated by TSA in fiscal year 2023-even though they met federal standards. That’s not a mistake. That’s policy. If you’re flying within the U.S. and you need CBD for anxiety or pain, bring it. But know you risk having it taken. If you’re flying internationally? Don’t even try. Many countries, including Japan, South Korea, and the UAE, ban CBD entirely-even with a prescription.

Traveler with green Sunflower Lanyard undergoing private screening while wearing medical device.

Controlled Substances Like Adderall, Xanax, and OxyContin Are Risky Abroad

If you’re taking Adderall, Xanax, or any other controlled substance, you’re fine flying domestically. But if you’re leaving the U.S.? You need to do your homework. Many countries treat these as illegal narcotics-even if you have a valid U.S. prescription.

Japan bans Adderall completely. Dubai will arrest you for carrying Xanax. Canada allows some controlled substances with a doctor’s letter, but only if they’re in original packaging. The CDC’s 2024 Yellow Book says travelers who don’t check destination rules risk detention, deportation, or even jail. Before you book your trip, look up your destination’s drug laws. The International Association for Medical Assistance to Travellers (IAMAT) has a free database built into the TSA app that lets you search over 200 countries. Use it.

Bring a Doctor’s Letter for Injectables and Controlled Drugs

If you’re flying with insulin pens, EpiPens, injectables, or anything that looks like a “controlled substance,” bring a letter from your doctor. It doesn’t need to be fancy. Just a short note on letterhead saying:

Your name
The medication and dosage
Why you need it
The doctor’s name, license number, and contact info

This isn’t required by TSA, but it cuts through confusion. One nurse who travels monthly for work told me she once got held up for 20 minutes because TSA thought her insulin pens were “suspicious devices.” She pulled out her letter. They apologized and waved her through. A doctor’s letter isn’t just helpful-it’s a shield.

Medical Devices Like Insulin Pumps and CGMs Are Allowed

If you use an insulin pump, continuous glucose monitor (CGM), or any other implanted or wearable medical device, you can bring it through security. TSA won’t make you remove it. But you should tell the officer before you go through the scanner. You can also ask for a pat-down instead of a body scan. You don’t need to prove you have the device-just say you use it.

For complex devices like an Omnipod or an external insulin pump, you can request a private screening. TSA’s Cares program (1-855-787-2227) lets you schedule special assistance 72 hours in advance. This isn’t just for wheelchairs or service animals-it’s for anyone with a medical device that needs extra care.

Don’t Freeze Your Meds Unless You Have to

If you need to keep your meds cold-like insulin or some biologics-you can bring frozen gel packs. But they must be completely frozen when you get to security. If they’re even slightly melted, TSA might take them. You can also use insulated bags, but don’t pack dry ice unless you’re flying with a medical provider who’s trained to handle it. Most travelers don’t need dry ice. Just pack your meds in a small cooler with ice packs, and declare them like any other medication.

Contrasting scene: ruined meds in checked bag vs. safe carry-on meds with international travel warnings.

TSA PreCheck Makes This Easier

If you have TSA PreCheck, you’re lucky. You don’t have to take your liquids out of your bag-including your meds. You can leave your pills, creams, and syrups in your carry-on. Just walk through the scanner like normal. That’s a huge time-saver. As of November 2024, over 28 million travelers have TSA PreCheck. If you fly more than twice a year, it’s worth the $78 fee. Apply at https://www.tsa.gov/precheck.

The Sunflower Lanyard Helps If You Need Extra Time

If you have a hidden disability-like anxiety, chronic pain, or a neurological condition-you might need more time or help explaining your meds. TSA now offers the Sunflower Lanyard program at 45 major U.S. airports. It’s a discreet green lanyard you wear that tells officers you need extra support. You don’t need to show a doctor’s note. Just ask for one at the airport’s customer service desk. It’s been a game-changer for people who get overwhelmed in crowded security lines.

What Happens If TSA Confiscates Your Medicine?

If your meds get taken, don’t argue. It won’t help. Ask for a supervisor. Ask why it was confiscated. If it was a CBD product, you might get a receipt with a claim form. You can request it back later-but most are destroyed. If it was a prescription you had in original packaging, that’s a mistake. File a complaint with TSA at https://www.tsa.gov/contact-center. They track these things. In 2023, over 500 complaints were filed about medication confiscations. Many led to policy reviews.

Final Checklist Before You Fly

✅ All meds in original bottles with your name on them
✅ No meds in checked luggage
✅ Liquid meds declared at checkpoint
✅ Doctor’s letter for injectables or controlled substances
✅ CBD products? Only if you’re okay risking confiscation
✅ Destination country rules checked (use IAMAT or CDC Yellow Book)
✅ TSA PreCheck? Use it
✅ Sunflower Lanyard? Request one if you need it

Flying with meds isn’t hard if you plan ahead. The rules are clear. The problem is the noise-misinformation online, rumors about “2025 rules,” and stories of people getting stopped. Most of those cases? They happened because someone skipped the basics. Do the basics. You’ll breeze through security. And your medicine? It’ll be waiting for you when you land.

Comments

Shannara Jenkins

2 Dec, 2025

Just flew last week with my insulin and honestly, this post saved me. I kept my pens in the original box, declared them upfront, and breeze right through. No drama. TSA agent even said 'good job'-which, you know, never happens. 😊
Roger Leiton

2 Dec, 2025

YES. I used to toss my pills into a pill organizer like a pro… until I got held up for 22 minutes because my ID said 'R. Leiton' and the bottle said 'Roger'. Never again. Original bottles FTW. 🙌
Elizabeth Grace

4 Dec, 2025

I hate how they treat CBD like it’s cocaine. I have a prescription for it in California and still got it taken at O’Hare. Like… I’m not trying to get high, I’m trying to sleep. Why does this feel like punishment?
Laura Baur

6 Dec, 2025

Let’s be honest-this whole system is a performative farce. The TSA doesn’t care about your health; they care about optics. They confiscate CBD because it’s politically inconvenient, not because it’s dangerous. And don’t get me started on the ‘original packaging’ rule-it’s a relic from the pre-digital age where pharmacists still stamped bottles by hand. We live in 2025. Why are we still treating medicine like contraband? It’s not about safety-it’s about control. And frankly, it’s dehumanizing.
Jack Dao

7 Dec, 2025

Anyone who flies with meds in checked luggage deserves what they get. If you're dumb enough to put your insulin in a suitcase, don't cry when it melts. This isn't rocket science. Basic responsibility, people.
dave nevogt

7 Dec, 2025

I’ve flown with a CGM for six years. The first time I told an officer I had a medical device, they looked at me like I was speaking a foreign language. Now I just say, ‘I’m diabetic, this is my monitor,’ and they nod. No paperwork. No fuss. It’s funny how simple it becomes when you stop overthinking it. The system isn’t broken-it’s just poorly communicated. This post? It’s the kind of clarity we need more of.
Ella van Rij

8 Dec, 2025

Oh wow, a 2025 guide. Did you get this from the TSA’s crystal ball? Because last I checked, TSA’s website still says ‘2024.’ But sure, let’s pretend we’re living in the future where everything’s perfect. 🙄
Jay Everett

10 Dec, 2025

Just want to add: if you’re flying internationally with Adderall or Xanax, DO NOT rely on the TSA app alone. I got flagged in Amsterdam because my doctor’s letter didn’t have a notarized seal. Turns out the Dutch require it. I had to email my doc at 3 a.m. and get it re-sent with a wet signature. Took 90 minutes. Don’t be me. Double-check EVERY country’s rules-even if they’re ‘friendly’ to Americans. The world doesn’t care about your U.S. prescription. 💪
Paul Keller

12 Dec, 2025

One thing no one talks about: the Sunflower Lanyard. I’ve got PTSD from airport security. Last year, I broke down crying because I couldn’t explain my anxiety meds fast enough. I got the lanyard this year. No one asked questions. No one stared. I just walked through. It’s not a gimmick-it’s a lifeline. If you need it, take it. No shame.
Steve Enck

14 Dec, 2025

While the logistical advice here is largely sound, one must interrogate the epistemological foundation of TSA policy itself. The agency operates under a paradigm of pre-emptive suspicion, wherein the burden of proof is not on the state to justify intrusion, but on the citizen to justify innocence. The requirement to declare medication, while pragmatically useful, reinforces a broader societal apparatus of surveillance capitalism. We are not merely traveling-we are being vetted. The original packaging rule? It is not about safety-it is about the commodification of identity through pharmaceutical branding. One’s body becomes a site of bureaucratic verification. The doctor’s letter, the lanyard, the PreCheck-these are not solutions. They are accommodations within a system designed to make us feel safe while keeping us compliant. And yet… we still comply. Why? Because we have no other choice.